William R Wagner (editor), Shelly E. Sakiyama-Elbert (editor), Guigen Zhang (editor), Michael J. Yaszemski (editor) - Biomaterials Science_ An Introduction to Materials in Medicine-Academic Press (202

Index

A

A disintegrin and metalloproteinases with thrombospondin motifs (ADAMTS),

706

a-SiC. See Amorphous silicon carbide (a-SiC)

A-V shunts system. See Arteriovenous shunts system (A-V shunts system)

AA. See Acrylic acid (AA)

AAA. See Abdominal aortic aneurysm (AAA) AAc. See Acrylic acid (AA)

AAm. See Acrylamide (AAm)

AAT. See Acellular adipose tissue (AAT)

A—B block copolymer, 85

A—B—C triblock copolymer, 85 Abdominal aortic aneurysm (AAA), 1038-1039 Abraxane, 470-471 Absorbable collagen sponge (ACS), 86lb-862b

Absorbable sutures, 1188, 1193 AC. See Alternating current (AC)

Ac4ManAz (mannose derivative), 470

ACA. See Affordable Care Act (ACA) Accommodation, 1135-1136, 1140 Accommodative IOLs, 1142

ACE. See Angiotensin-converting enzyme (ACE)

Acellular

dermal scaffolds, 1174 human dermal matrix, 386 porcine urinary bladder, 387 Acellular adipose tissue (AAT), 1404 for soft tissue injuries, 1404 lipoaspirate, 1404

Acid

acid-etch bonding to enamel, 1184 acid-base

dental cement, 1183, 1184f reactions, 1182 proteases, 698

ACL. See Anterior cruciate ligament (ACL) Acquired immunity. See Adaptive immunity Acrylamide (AAm), 146, 434^35 Acrylic acid (AA), 193, 434^35 Acrylic hydrogels, 157-158

AcrySof intraocular lens, 1141

ACS. See Absorbable collagen sponge (ACS)

ActiCoat, 1171t, 1173

Actifuse ABX, 294, 296f

Actin fibers, 1340

Action, radiation-based techniques, 1432 Activated charcoal, 333 Active caspase-1, 1106 Active materials, 522-528. See also Inert materials.

heparinization, 522-526

antithrombin III-binding pentasaccharide of heparin, 524f covalently bound heparin, 525-526 ionically bound heparin and con-

trolled-release systems, 523-525 immobilization

of antiplatelet agents, 527 of fibrinolytic agents, 527-528 thrombin inhibition without heparin,

526-527

Active targeting, 470, 1254-1257 antibodies, 1255 aptamers, 1255-1257 carbohydrates, 1257 ligands, 1256t peptides, 1255 proteins, 1255 small molecules, 1257 Active tissue targeting via anchored click

chemistry (ATTACK), 470-471, 471f Acute inflammation, 697 Acute toxicity, 465^66, 871-872 N-Acyl-homoserine lactones (AHLs), 834 ADAMTS. See A disintegrin and metalloproteinases with thrombospondin motifs (ADAMTS) Adaptation, 693

Adaptive immunity, 697, 757-772. See also Innate immunity.

B cell and antibody recognition, 762 cell-mediated immunity, 760 components, 757-760 CTLs, 760

effector pathways in, 763-764 helper T cells, 760-761

humoral immunity, 760 immune regulation and tolerance,

766-768

immune response to pathogens, 765-766 immunological memory, 764, 764f intersection of biomaterials and immunology, 768-772 recognition in, 762 T cell recognition, 762-763 ADCC. See Antibody-dependent cell-mediated cytotoxicity (ADCC)

ADCs. See Antibody-drug conjugates (ADCs)

Addition polymerization, 95-96 Additive manufacturing (AM), 232, 300, 485-486, 623, 1296 bioprinting, 630-632 medical applications of 3D printing, 632-634

personalized drug delivery systems,

634-635

3D printing modalities, 623-630 Additives, 591, 1322-1323 Adenosine diphosphate (ADP), 802 Adenosine triphosphate (ATP), 691 Adherent cells, 663-664 Adhesion, 824-825. See also Bacterial adhesion; Focal adhesions. ligands, 596 proteins, 406

depletion studies, 647-648 effect on cellular interactions, 645-649 preadsorption with purified adhesion proteins, effects of, 646-647 receptor activity with antibodies, inhibition of, 648-649 receptors, 706-707 Adhesive(s)

bioadhesives, 1187 biomimetic approaches, 1188 cyanoacrylate esters, 1186-1187 fibrin sealants, 1187 hard-tissue adhesives, 1182-1186 acid-etch bonding to enamel, 1184 aging and stability of bonded interface, 1186

Note: Page numbers followed by “f” indicate figures and “t” indicate tables and “b” indicate boxes.

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